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J Clin Periodontol. 2018 Aug;45(8):959-967. doi: 10.1111/jcpe.12922. Epub 2018 Jun 21.

Effect of guava and vitamin C supplementation on experimental gingivitis: A randomized clinical trial.

Author information

1
Department of Periodontology, Padjadjaran State University, Bandung, Indonesia.
2
Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands.

Abstract

OBJECTIVE:

To study the effect of guava and synthetic vitamin C on the development of gingival inflammation during experimental gingivitis.

MATERIAL AND METHODS:

Participants were randomly assigned to three groups supplemented daily with either 200 g guava, 200 mg synthetic vitamin C or water. The study included a 14 days pre-experimental period with oral hygiene instructions, scaling, prophylaxis and supplementation. Thereafter, experiment gingivitis was initiated, while continuing supplementation. At baseline, Day 7 and Day 14 of experimental gingivitis, Plaque Index (PlI) and Gingival Index (GI) were assessed. During the entire study, dietary fruit/vegetables intake was minimal.

RESULTS:

PlI increased in guava, vitamin C and control group (ΔPlI: 1.30, 1.61 and 1.79, respectively). However, the guava group developed significantly less plaque compared to the control group. The GI increase in both guava and vitamin C group was significantly less than the increase in the control group (ΔGI: 0.10, 0.24 and 0.87, respectively).

CONCLUSION:

In a population of young nonsmoking adults, consumption of either 200 g guava/day or 200 mg synthetic vitamin C/day, prior to and during the oral hygiene abstention period, has a preventive effect on the development of experimental gingivitis as compared to the control group that developed the usual amount of experimental gingivitis.

KEYWORDS:

experimental gingivitis; guava fruit; supplementation; vitamin C

PMID:
29757462
DOI:
10.1111/jcpe.12922

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