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Trends Parasitol. 2018 Jun;34(6):450-452. doi: 10.1016/j.pt.2018.04.006. Epub 2018 May 8.

Sex in Plasmodium falciparum: Silence Play between GDV1 and HP1.

Author information

1
School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
2
Department of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA 92521, USA.
3
School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK. Electronic address: rita.tewari@nottingham.ac.uk.

Abstract

Understanding how malaria parasites commit to sexual development is key to the development of transmission-blocking strategies. Recent work by Filarsky and colleagues extends our understanding of the molecular mechanisms driving this process by characterizing an early factor in gametocytogenesis, and showing how this fits neatly into our current knowledge of sexual commitment.

PMID:
29752147
PMCID:
PMC6122602
DOI:
10.1016/j.pt.2018.04.006
[Indexed for MEDLINE]
Free PMC Article

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