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Nutrients. 2018 May 3;10(5). pii: E563. doi: 10.3390/nu10050563.

Effects of Whey Protein Supplementation Pre- or Post-Resistance Training on Muscle Mass, Muscular Strength, and Functional Capacity in Pre-Conditioned Older Women: A Randomized Clinical Trial.

Author information

1
Federal Institute of Science and Technology of Mato Grosso, Highway BR-364, Km 329, Cuiabá, Mato Grosso 78106-970, Brazil. hellen.nabuco@svc.ifmt.edu.br.
2
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. hellen.nabuco@svc.ifmt.edu.br.
3
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. crisielitomeleri@gmail.com.
4
Faculty of Physical Education, University of Campinas, Érico Veríssimo avenue, Campinas, São Paulo 13083-970, Brazil. crisielitomeleri@gmail.com.
5
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. juniornutricao@hotmail.com.
6
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. rodrigo.r.fernandes@gmail.com.
7
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. edilainefungari@gmail.com.
8
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. melissa.antunes@hotmail.com.
9
Center for Research in Health Sciences, University of Northern Paraná, Paris Avenue, Londrina, Paraná 86041-140, Brazil. alex-silvaribeiro@hotmail.com.
10
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. denict@uel.br.
11
Department of Physical Education, Faculty of Physical Education and Sport, State University of Londrina, Londrina, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. denict@uel.br.
12
Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Estrada da Costa, Cruz Quebrada, Dafundo 1499-002, Portugal. analiza@fmh.ulisboa.pt.
13
Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Estrada da Costa, Cruz Quebrada, Dafundo 1499-002, Portugal. lbsardinha55@gmail.com.
14
Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. edilsoncyrino@gmail.com.
15
Department of Physical Education, Faculty of Physical Education and Sport, State University of Londrina, Londrina, Highway Celso Garcia Cid, Londrina, Paraná 86057-970, Brazil. edilsoncyrino@gmail.com.

Abstract

Aging is associated with sarcopenia and dynapenia, with both processes contributing to functional dependence and mortality in older adults. Resistance training (RT) and increased protein intake are strategies that may contribute to health improvements in older adults. Therefore, the aim was to investigate the effects of whey protein (WP) supplementation consumed either immediately pre- or post-RT on skeletal muscle mass (SMM), muscular strength, and functional capacity in pre-conditioned older women. Seventy older women participated in this investigation and were randomly assigned to one of three groups: whey protein pre-RT and placebo post-RT (WP-PLA, n = 24), placebo pre-RT and whey protein post-RT (PLA-WP, n = 23), and placebo pre- and post-RT (PLA-PLA, n = 23). Each group ingested 35 g of WP or PLA. The RT program was carried out over 12 weeks (three times per week; 3 &times; 8⁻12 repetition maximum). Body composition, muscular strength, functional capacity, and dietary intake were assessed pre- and post-intervention. Two-way analysis of covariance (ANCOVA) for repeated measures, with baseline scores as covariates were used for data analysis. A time vs. group interaction (p < 0.05) was observed with WP-PLA and PLA-WP presenting greater increases compared with PLA-PLA for SMM (WP-PLA = 3.4%; PLA-WP = 4.2%; PLA-PLA = 2.0%), strength (WP-PLA = 8.1%; PLA-WP = 8.3%; PLA-PLA = 7.0%), and the 10-m walk test (WP-PLA = &minus;10.8%; PLA-WP = &minus;11.8%; PLA-PLA = &minus;4.3%). Whey protein supplementation was effective in promoting increases in SMM, muscular strength, and functional capacity in pre-conditioned older women, regardless of supplementation timing. This trial was registered at ClinicalTrials.gov: NCT03247192.

KEYWORDS:

aging; hypertrophy; protein timing; strength training

PMID:
29751507
PMCID:
PMC5986443
DOI:
10.3390/nu10050563
[Indexed for MEDLINE]
Free PMC Article

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