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Euro Surveill. 2018 May;23(18). doi: 10.2807/1560-7917.ES.2018.23.18.18-00197.

Prolonged detection of dengue virus RNA in the semen of a man returning from Thailand to Italy, January 2018.

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These authors contributed equally to this work.
National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, Rome, Italy.


This study reports the presence of dengue virus RNA in longitudinally collected semen samples of a previously healthy Caucasian man, returning to Italy from Thailand with primary dengue fever, up to 37 days post-symptom onset, when viraemia and viruria were undetectable. This finding, coupled with the evidence of dengue virus negative-strand RNA, an indirect marker of ongoing viral replication, in the cellular fraction of semen, indicates a need to further investigate possible sexual transmission.


Flaviviridae; dengue virus; semen shedding; sexual transmission; vector-borne infections

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