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J Am Coll Cardiol. 2018 May 8;71(18):2015-2040. doi: 10.1016/j.jacc.2017.12.068.

Coronary Artery Disease in Patients ≥80 Years of Age.

Author information

1
New York-Presbyterian Hospital and the Columbia University Medical Center, New York, New York.
2
Mayo Clinic College of Medicine, Rochester, Minnesota.
3
Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
4
New York-Presbyterian Hospital and the Columbia University Medical Center, New York, New York; Cardiovascular Research Foundation, New York, New York. Electronic address: gs2184@columbia.edu.

Abstract

Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients ≥80 years of age. Nonetheless, older patients have typically been under-represented in cardiovascular clinical trials. Understanding the pathophysiology, epidemiology, and optimal means of diagnosis and treatment of CAD in older adults is crucial to improving outcomes in this high-risk population. A patient-centered approach, taking into account health status, functional ability and frailty, cognitive skills, and patient preferences is essential when caring for older adults with CAD. The present systematic review focuses on the current knowledge base, gaps in understanding, and directions for future investigation pertaining to CAD in patients ≥80 years of age.

KEYWORDS:

coronary artery disease; geriatric cardiology; octogenarians

PMID:
29724356
DOI:
10.1016/j.jacc.2017.12.068

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