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J Clin Periodontol. 2018 Jul;45(7):791-798. doi: 10.1111/jcpe.12909. Epub 2018 May 28.

Chronic periodontitis is associated with erectile dysfunction. A case-control study in european population.

Author information

1
Department of Periodontics, School of Dentistry, University of Granada, Granada, Spain.
2
Department of Preventive and Community Dentistry, School of Dentistry, University of Granada, Granada, Spain.
3
Urology Unit, Granada University Hospital Complex, Granada, Spain.

Abstract

AIM:

To determine the association between chronic periodontitis and erectile dysfunction adjusting for biochemical markers and other comorbidities.

METHODS:

A case-control study was conducted on 158 male patients; 80 cases with erectile dysfunction according to the International Index of Erectile Function and 78 controls. Sociodemographic data were gathered, and a periodontal examination was performed. Testosterone, lipid profile, C-reactive protein and glycaemic parameters were assessed. All variables were compared between groups, and multivariate logistic regression analyses were performed.

RESULTS:

74% of the cases were diagnosed with chronic periodontitis. Number of sites with pocket probing depth 4-6 mm (p = 0.05) and number of sites with clinical attachment loss >3 mm (p < 0.01) were higher in the cases. Triglycerides (p < 0.01), C-reactive protein (p = 0.02) and glycosylated haemoglobin (p = 0.04) were also higher in the cases. Logistic regression showed that patients with chronic periodontitis were more likely to have erectile dysfunction (OR=2.17; 95% CI (1.06-4.43); p = 0.03) independently of other confounders.

CONCLUSION:

Patients with erectile dysfunction showed worse periodontal condition. Chronic periodontitis seems to play a key role as a risk factor in the pathogenesis of erectile dysfunction independently of other morbidities.

KEYWORDS:

cardiovascular diseases; case-control studies; chronic periodontitis; erectile dysfunction; periodontics

PMID:
29723438
DOI:
10.1111/jcpe.12909

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