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Curr Oncol. 2018 Apr;25(2):139-148. doi: 10.3747/co.25.3790. Epub 2018 Apr 30.

Intravenous vitamin C in the supportive care of cancer patients: a review and rational approach.

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Salish Cancer Center, Fife, WA, U.S.A.
Naturopathic Specialists, Scottsdale, AZ, U.S.A.
Department of Research and Clinical Epidemiology, Ottawa Integrative Cancer Centre, Ottawa, ON.
Department of Medical Oncology, Cancer Treatment Centers of America, Philadelphia, PA, U.S.A.


This article reviews intravenous vitamin C (IV C) in cancer care and offers a rational approach to enable medical oncologists and integrative practitioners to safely provide IV C combined with oral vitamin C to patients. The use of IV C is a safe supportive intervention to decrease inflammation in the patient and to improve symptoms related to antioxidant deficiency, disease processes, and side effects of standard cancer treatments. A proposed rationale, together with relevant clinical safety considerations for the application of IV C in oncologic supportive care, is provided.


Vitamin C deficiency; ascorbate; intravenous vitamin C; quality of life; supportive care

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