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J Korean Med Sci. 2018 Apr 12;33(18):e132. doi: 10.3346/jkms.2018.33.e132. eCollection 2018 Apr 30.

Characteristics and Incidence Trends for Pediatric Inflammatory Bowel Disease in Daegu-Kyungpook Province in Korea: a Multi-Center Study.

Hong SJ1,2, Cho SM3,2, Choe BH4,2, Jang HJ5,2, Choi KH6,2, Kang B4,2, Kim JE4,2, Hwang JH7.

Author information

1
Department of Pediatrics, Daegu Catholic University School of Medicine, Daegu, Korea.
2
Crohn's and Colitis Association in Daegu-Gyeongbuk (CCAiD), Daegu, Korea.
3
Department of Pediatrics, Dongguk University School of Medicine, Gyeongju, Korea.
4
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
5
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea.
6
Department of Pediatrics, Yeungnam University School of Medicine, Daegu, Korea.
7
Department of Preventive Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.

Abstract

Background:

Inflammatory bowel disease (IBD) is a heterogeneous chronic disease of unknown etiology. Although it is an important disease that shows a rapid increase in pediatric population, there are no pediatric studies that represent a specific region in Korea. Therefore, we studied the epidemiological and phenotypic characteristics of pediatric IBD in Daegu-Kyungpook province, Korea.

Methods:

We included 122 children with pediatric IBD initially diagnosed at one of four university hospitals in Daegu-Kyungpook province between July 2010 and June 2016. We investigated the incidence trends, and the clinical characteristics at diagnosis were compared by Paris classification.

Results:

We included 122 children: 98 with Crohn's disease (CD) and 24 with ulcerative colitis (UC). The average age at diagnosis was 13.6 years for IBD. The incidence shows an increasing trend. CD showed a significant increase, whereas UC appears to be increasing slowly. In CD, there was a significant male predominance. For disease activity sites, the most common location was L3 (77.6%), indicating ileocolonic involvement as the major type. B1 (88.8%) was the most common disease behaviors type. Perianal disease was noted in 43 patients (43.9%) and weight loss in 60 (61.2%). In UC, E4 (58.4%) was the most common disease activity site, indicating pancolonic involvement as the major type.

Conclusion:

We found that the number of pediatric patients with IBD is increasing rapidly in Daegu-Kyungpook province in Korea. Our study also revealed that the characteristics of pediatric IBD in our province differ somewhat from those of pediatric IBD in Western countries.

KEYWORDS:

Adolescent; Child; Crohn's disease; Inflammatory Bowel Disease; Korea; Ulcerative Colitis

PMID:
29713253
PMCID:
PMC5920122
DOI:
10.3346/jkms.2018.33.e132
[Indexed for MEDLINE]
Free PMC Article

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