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J Korean Med Sci. 2018 Apr 12;33(18):e132. doi: 10.3346/jkms.2018.33.e132. eCollection 2018 Apr 30.

Characteristics and Incidence Trends for Pediatric Inflammatory Bowel Disease in Daegu-Kyungpook Province in Korea: a Multi-Center Study.

Hong SJ1,2, Cho SM3,2, Choe BH4,2, Jang HJ5,2, Choi KH6,2, Kang B4,2, Kim JE4,2, Hwang JH7.

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Department of Pediatrics, Daegu Catholic University School of Medicine, Daegu, Korea.
Crohn's and Colitis Association in Daegu-Gyeongbuk (CCAiD), Daegu, Korea.
Department of Pediatrics, Dongguk University School of Medicine, Gyeongju, Korea.
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea.
Department of Pediatrics, Yeungnam University School of Medicine, Daegu, Korea.
Department of Preventive Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.



Inflammatory bowel disease (IBD) is a heterogeneous chronic disease of unknown etiology. Although it is an important disease that shows a rapid increase in pediatric population, there are no pediatric studies that represent a specific region in Korea. Therefore, we studied the epidemiological and phenotypic characteristics of pediatric IBD in Daegu-Kyungpook province, Korea.


We included 122 children with pediatric IBD initially diagnosed at one of four university hospitals in Daegu-Kyungpook province between July 2010 and June 2016. We investigated the incidence trends, and the clinical characteristics at diagnosis were compared by Paris classification.


We included 122 children: 98 with Crohn's disease (CD) and 24 with ulcerative colitis (UC). The average age at diagnosis was 13.6 years for IBD. The incidence shows an increasing trend. CD showed a significant increase, whereas UC appears to be increasing slowly. In CD, there was a significant male predominance. For disease activity sites, the most common location was L3 (77.6%), indicating ileocolonic involvement as the major type. B1 (88.8%) was the most common disease behaviors type. Perianal disease was noted in 43 patients (43.9%) and weight loss in 60 (61.2%). In UC, E4 (58.4%) was the most common disease activity site, indicating pancolonic involvement as the major type.


We found that the number of pediatric patients with IBD is increasing rapidly in Daegu-Kyungpook province in Korea. Our study also revealed that the characteristics of pediatric IBD in our province differ somewhat from those of pediatric IBD in Western countries.


Adolescent; Child; Crohn's disease; Inflammatory Bowel Disease; Korea; Ulcerative Colitis

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