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Angew Chem Int Ed Engl. 1998 Sep 18;37(17):2320-2328. doi: 10.1002/(SICI)1521-3773(19980918)37:17<2320::AID-ANIE2320>3.0.CO;2-2.

The Identification of the Sodium-Potassium Pump (Nobel Lecture).

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1
Department of Biophysics, University of Århus, Ole Worms Allé 185, DK-8000 Aarhus C (Denmark), Fax: (+45) 8612-9599.

Abstract

Deemed too provocative, the word "pump" was omitted in the title of the 1957 publication "The Influence of Some Cations on an Adenosine Triphosphatase from Peripheral Nerves", in which J. C. Skou showed that an ATPase in the membrane of crab nerves had such characteristics from the point of view of substrate ATP and effect of Na and K that it was reasonable to suggest that it was involved in the active transport of Na across the cell membrane.

KEYWORDS:

ATP; Ion transport; Membranes; Nobel lecture; Sodium-potassium pump

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