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Microb Pathog. 2018 Aug;121:70-76. doi: 10.1016/j.micpath.2018.04.043. Epub 2018 Apr 27.

Bacterial diversity in the feces of dogs with CPV infection.

Author information

1
College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou, Guangdong Province, 510642, People's Republic of China.
2
College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China.
3
College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou, Guangdong Province, 510642, People's Republic of China. Electronic address: zhoupei@scau.edu.cn.
4
College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou, Guangdong Province, 510642, People's Republic of China. Electronic address: shoujunli@scau.edu.cn.

Abstract

Canine parvovirus (CPV) is a contagious disease in dogs that has high morbidity and mortality. In cases of infection, the pups tend to have a higher mortality and more severe clinical symptoms than the adult dogs because the dehydration is difficult for pups to bear. Following the natural infection, there is a rapid antibody response neutralizing the extracellular virus. As a result, virus titers in tissue and feces become markedly reduced. Hence, it is important to have an effective symptomatic therapy of supporting animals to survive in the early stages of CPV infection. Furthermore, the co-infection with bacteria could increase the severity of lesions and clinical signs as well. In this paper, we obtained the bacterial diversity in feces of CPV infected dogs with the enrichment of five bacteria genera (Shigella, Peptoclostridium, Peptostreptococcus, Streptococcus, Fusobacterium). These microorganisms may partly result in the intestinal pathology of the infection. In summary, the discussion of the bacterial biodiversity in feces of CPV infected dogs provides further insights into the pathology of CPV disease and the targets of developing more effective treatment strategies.

KEYWORDS:

Bacterial diversity; CPV; Dogs; Feces

PMID:
29709688
DOI:
10.1016/j.micpath.2018.04.043
[Indexed for MEDLINE]

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