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Curr Opin Ophthalmol. 2018 Jul;29(4):365-372. doi: 10.1097/ICU.0000000000000485.

Adenoviral keratitis: a review of the epidemiology, pathophysiology, clinical features, diagnosis, and management.

Author information

1
Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.

Abstract

PURPOSE OF REVIEW:

Adenoviral keratitis is a common and bothersome ocular infection that produces a lot of burden on healthcare systems and patients. The goal of this article is to provide a review of the topic, with an emphasis on current attempts at advancing strategies in diagnosis and management.

RECENT FINDINGS:

Sixty-eight articles and one textbook published on adenoviral keratitis were reviewed. The findings on the epidemiology, pathophysiology, clinical features, diagnosis, and management were summarized. Any contradicting opinions for which the literature was unclear were either omitted or recorded as lacking strong evidence.

SUMMARY:

Although significant effort has been made to develop new methods for diagnosis and management, adenoviral keratitis is predominantly diagnosed clinically with prevention being the mainstay of management. The use of newer DNA analysis techniques and topical anti-inflammatory agents for treatment of corneal infiltrates show promising results, but a better understanding of the pathogenesis and clinical features can lead to more targeted methods of diagnosis and therapy.

PMID:
29708932
DOI:
10.1097/ICU.0000000000000485
[Indexed for MEDLINE]

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