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J Cataract Refract Surg. 2018 Apr;44(4):471-478. doi: 10.1016/j.jcrs.2018.02.015. Epub 2018 Apr 25.

Repeatability of automatic measurements by a new anterior segment optical coherence tomographer combined with Placido topography and agreement with 2 Scheimpflug cameras.

Author information

1
From G.B. Bietti Eye Foundation IRCCS (Savini, Schiano-Lomoriello), Rome, Italy; Stein Eye Institute (Hoffer), University of California, Los Angeles, and St. Mary's Eye Center (Hoffer), Santa Monica, California, USA. Electronic address: giacomo.savini@alice.it.
2
From G.B. Bietti Eye Foundation IRCCS (Savini, Schiano-Lomoriello), Rome, Italy; Stein Eye Institute (Hoffer), University of California, Los Angeles, and St. Mary's Eye Center (Hoffer), Santa Monica, California, USA.

Abstract

PURPOSE:

To evaluate the repeatability of automatic measurements by a new anterior segment optical coherence tomographer (AS-OCT) combined with Placido topography and their agreement with those provided by 2 rotating Scheimpflug cameras.

SETTING:

G.B. Bietti Foundation IRCCS, Rome, Italy.

DESIGN:

Evaluation of a diagnostic test instrument.

METHODS:

Unoperated eyes and eyes with previous myopic excimer laser surgery were analyzed. Three consecutive scans were acquired with an AS-OCT device (MS-39) and 1 with 2 rotating Scheimpflug cameras (Pentacam HR and Sirius). The following parameters were evaluated: simulated keratometry, posterior and total corneal power, total corneal astigmatism, corneal asphericity, thinnest corneal thickness, central epithelial thickness, corneal diameter, and aqueous depth. Repeatability was assessed using test-retest variability, the coefficient of variation (CoV), and the intraclass correlation coefficient; agreement was assessed by the 95% limits of agreement.

RESULTS:

The study comprised 96 unoperated eyes and 43 eyes with previous myopic excimer laser surgery. High repeatability was achieved in both groups, as shown by a CoV less than 1.0% for most parameters. The repeatability of epithelial thickness was slightly lower than that of the whole corneal thickness, although the CoV was still good (1.87% in unoperated eyes; 3.28% in post-refractive surgery eyes). Moderate repeatability was found for total corneal astigmatism measurements, with a CoV greater than 20.0%. Agreement with Scheimpflug cameras was high for aqueous depth and thinnest corneal thickness and moderate for most other parameters.

CONCLUSION:

The high repeatability of automatic measurements by the new AS-OCT device supports its use in clinical practice.

PMID:
29705008
DOI:
10.1016/j.jcrs.2018.02.015
[Indexed for MEDLINE]
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