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Bioinformatics. 2018 Oct 1;34(19):3377-3379. doi: 10.1093/bioinformatics/bty336.

Cluster Locator, online analysis and visualization of gene clustering.

Author information

1
Developmental Neurobiology, IIBCE, Montevideo, Uruguay.
2
Genome Analysis Platform, Derio, Spain.
3
Functional Genomics Unit, CIC bioGUNE, Derio, Spain.
4
CIBERehd, ISCIII, Madrid, Spain.
5
Zoology Department, Stockholm University, Stockholm, Sweden.

Abstract

Summary:

Genes sharing functions, expression patterns or quantitative traits are not randomly distributed along eukaryotic genomes. In order to study the distribution of genes that share a given feature, we present Cluster Locator, an online analysis and visualization tool. Cluster Locator determines the number, size and position of all the clusters formed by the protein-coding genes on a list according to a given maximum gap, the percentage of gene clustering of the list and its statistical significance. The output includes a visual representation of the distribution of genes and gene clusters along the reference genome.

Availability and implementation:

Cluster Locator is freely available at http://clusterlocator.bnd.edu.uy/.

Supplementary information:

Supplementary data are available at Bioinformatics online.

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