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J Gastroenterol Hepatol. 2018 Oct;33(10):1707-1716. doi: 10.1111/jgh.14268. Epub 2018 Jun 12.

Consensus and contentious statements on the use of probiotics in clinical practice: A south east Asian gastro-neuro motility association working team report.

Author information

1
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
2
Gleneagles Hospital, Singapore.
3
Camden Medical Centre and Endocrinology Service, Department of Paediatric Medicine, KK Hospital, Singapore.
4
Department of Gastroenterology and Hepatology, General Hospital, Singapore.
5
Duke-NUS Medical School, Singapore.
6
Department of Paediatrics Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
7
Division of Gastroenterology and Hepatology, National University Health System, Singapore.
8
Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore.
9
Ipoh Gastro Centre, Ipoh, Malaysia.
10
Division of Gastroenterology and Hepatology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
11
Unit of Gastroenterology and Hepatology, Department of Medicine, The National University of Malaysia Medical Centre, Cheras, Kuala Lumpur, Malaysia.
12
Nutrition and Dietetics, KK Women's and Children's Hospital, Singapore.
13
Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
14
Section of Gastroenterology, University of Santo Tomas Hospital, Manila, Philippines.
15
Department of Internal Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
16
GI Motility Research Unit, Division of Gastroenterology, Department of Medicine Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
17
School of Medical Sciences, University of Science Malaysia, Kota Bharu, Kelantan, Malaysia.
18
Medical Center Manila, Manila, Philippines.
19
Klinik Pakar Y&C, Menglembu, Perak, Malaysia.
20
Klnic Chong, Slim River, Perak, Malaysia.
21
Hospital Fatimah, Ipoh, Malaysia.

Abstract

The concept of consuming microorganisms in the treatment of a medical condition and in health maintenance has gained much attraction, giving rise to an abundance of medical claims and of health supplements. This study identified relevant clinical questions on the therapeutic use of probiotics and reviewed the literature in irritable bowel syndrome, inflammatory bowel disease, impaired intestinal immunity, liver disease, intestinal infections, and common childhood digestive disorders. Statements were developed to address these clinical questions. A panel of experienced clinicians was tasked to critically evaluate and debate the available data. Both consensus and contentious statements are presented to provide to clinicians a perspective on the potential of probiotics and importantly their limitations.

KEYWORDS:

Asia; childhood; gastrointestinal; liver; obesity; probiotics

PMID:
29697855
DOI:
10.1111/jgh.14268
[Indexed for MEDLINE]

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