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Rev Med Inst Mex Seguro Soc. 2017;55(Suppl 2):S143-50.

Biomarkers in Chronic Kidney Disease

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Unidad de Investigación Médica en Enfermedades Nefrológicas, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México Correo electrónico: jrpaniaguas@gmail.com

Abstract

in English, Spanish

Chronic kidney disease (CKD) is an important public health problem. The classification of CKD by KDOQI and KDIGO and routine reports of the estimation of the glomerular filtration rate (eGFR), have resulted in a higher frequency in the diagnosis of CKD. Identification of CKD subjects and high risk of disease progression and cardiovascular disease (CVD) development is important. In clinical practice, proteinuria is the most sensitive marker of the progression of CKD, especially when combined with eGFR, but these have limitations. Therefore, the use of other early and sensitive biomarkers is required. Promising biomarkers are now being identified for the detection of CKD progression and its associated CVD morbidity and mortality. These are sensitive biomarkers of renal function, underlying pathophysiological processes and/or cardiovascular risk.

KEYWORDS:

Biomarkers; Renal Insufficiency, Chronic; Cardiovascular Diseases

PMID:
29697235
[Indexed for MEDLINE]

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