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Am J Ophthalmol. 1988 Aug 15;106(2):139-46.

Abnormal scleral findings in uveal effusion syndrome.

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1
Retina Service, Massachusetts Eye and Ear Infirmary, Boston 02114.

Abstract

We successfully treated a patient with uveal effusion syndrome and abnormal sclera with a partial-thickness sclerectomy. Part of the sclera was immediately cultured, and the excised sclera and the cultured cells were examined by electron microscopy. The sclera demonstrated increased glycosaminoglycan-like deposits between the scleral fibers. The cultured scleral cells showed large intracellular glycogen-like deposits, which were not seen in cells cultured from two control scleras. These findings may be the result of a metabolic defect, which causes a thick, impermeable sclera in some cases of uveal effusion.

PMID:
2969684
DOI:
10.1016/0002-9394(88)90825-2
[Indexed for MEDLINE]

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