Format

Send to

Choose Destination
Pediatr Transplant. 2018 Aug;22(5):e13196. doi: 10.1111/petr.13196. Epub 2018 Apr 25.

Outcomes of single kidney transplantation from pediatric donors: A single-center experience.

Jiang Y1,2,3, Song T1,2,3, Qiu Y1,2,3, Liu J1,2,3, Wang Z1,2,3, Wang X1,2,3, Huang Z1,2,3, Fan Y1,2,3, Wang L1,2,3, Lin T1,2,3.

Author information

1
Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
2
Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
3
Organ transplantation center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Abstract

Kidneys from pDDs are increasingly used to narrow the huge gap between incremental demand and static supply. However, there is still controversy on the clinical outcome of SKT from pDDs. We conducted a retrospective cohort study of 452 adult recipients in our center between March 2012 and February 2017. Outcomes of 3 groups, transplants with organs from pDDs (n=50), aDDs (n=207), and LDs (n=195), were compared. The mean age and weight of pDDs were 8.98 years (range 8 months-17 years) and 30.05 kg (range 8.2-55 kg), respectively. There was no difference in 1-year (96.0%, 98.1%, and 99.0%, respectively, P=.277) and 3-year patient survival (96.0%, 98.1%, and 99.0%, respectively, P=.277) or in 1-year (96.0%, 96.6%, and 98.5%, P=.307) and 3-year (96.0%, 96.6% and 97.9%, P=.437) graft survival. SCr, eGFR, and allograft size were similar among the 3 groups at 6th month post-transplant and thereafter. Incidence of DGF was higher in patients of the aDD group than those in the pDD group (22.7% vs 10.0%, P<.001), but there was no difference in AR and infection. SKT from pDDs to adult recipients is effective and safe with acceptable outcomes, and it will be a promising expansion to the donor pool.

KEYWORDS:

outcomes; pediatric donors; single kidney transplantation

PMID:
29696741
DOI:
10.1111/petr.13196
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center