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A A Pract. 2018 Oct 1;11(7):175-180. doi: 10.1213/XAA.0000000000000775.

When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report.

Author information

1
From the Department of Anesthesiology, Division of Critical Care Medicine.
2
Division of Cardiovascular Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland.
3
Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, Maryland.

Abstract

Angiotensin (AT) II is an endogenous hormone that acts on venous and arterial smooth muscle to cause vasoconstriction. Recent trials have sparked great interest in its ability to be used as a vasopressor for catecholamine-refractory hypotension. Herein, we describe the successful use of AT II in a patient with a colonic perforation with septic shock refractory to conventional treatment. After AT II initiation, there was an immediate reduction in catecholamine requirement, and the patient survived.

PMID:
29688923
DOI:
10.1213/XAA.0000000000000775
[Indexed for MEDLINE]

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