Format

Send to

Choose Destination
Circulation. 2018 Apr 24;137(17):1846-1860. doi: 10.1161/CIRCULATIONAHA.117.031264.

Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.

Author information

1
Hospital General Universitari Vall d'Hebron, CIBER-CV, Barcelona, Spain (A.E.).
2
Massachusetts General Hospital, Boston (E.M.I.).
3
University of Salerno, Italy (E.B.).
4
University of Pittsburgh, PA (T.G.G.).
5
University of Bologna, Italy (M.D.E.).
6
Robert-Bosch Krankenhaus, Stuttgart, Germany (U.S.).
7
University of Vienna, Austria (M.P.E.).
8
IRCCS Policlinico San Donato, Italy (S.T.).
9
Washington University School of Medicine, St. Louis, MO (A.C.B.).
10
Tromso University Hospital, Norway (T.M.).
11
Minneapolis Heart Institute, MN (K.M.H.).
12
University of Calgary Medical Centre, Alberta, Canada (S.H.).
13
Brigham and Women's Hospital, Boston, MA (P.O'G.).
14
University of Leicester, United Kingdom (T.S.).
15
The Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom (C.A.N.).
16
University of Michigan, Ann Arbor (K.A.E.). keagle@umich.edu.

Abstract

Acute aortic dissection (AAD) is a life-threatening condition associated with high morbidity and mortality rates, and it remains a challenge to diagnose and treat. The International Registry of Acute Aortic Dissection was established in 1996 with the mission to raise awareness of this condition and provide insights to guide diagnosis and treatment. Since then, >7300 cases have been included from >51 sites in 12 countries. Although presenting symptoms and physical findings have not changed significantly over this period, the use of computed tomography in the diagnosis has increased, and more patients are managed with interventional procedures: surgery in type A AAD and endovascular therapy in type B AAD; with these changes in care, there has been a significant decrease in overall in-hospital mortality in type A AAD but not in type B AAD. Herein, we summarized the key lessons learned from this international registry of patients with AAD over the past 20 years.

KEYWORDS:

aneurysm, dissecting; diagnosis; endovascular procedures; tomography, x-ray computed; treatment outcome

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center