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Chem Sci. 2017 Dec 6;9(4):1042-1049. doi: 10.1039/c7sc04422d. eCollection 2018 Jan 28.

Enantioselective cellular localisation of europium(iii) coordination complexes.

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1
Department of Chemistry , Durham University , South Road , Durham , DH1 3LE , UK . Email: david.parker@dur.ac.uk.

Abstract

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(iii) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.

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