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Neuron. 2018 Apr 18;98(2):246-248. doi: 10.1016/j.neuron.2018.04.005.

Symmetric Stem Cell Division at the Heart of Adult Neurogenesis.

Author information

1
Biozentrum, University of Basel, Basel CH-4056, Switzerland.
2
Biozentrum, University of Basel, Basel CH-4056, Switzerland. Electronic address: fiona.doetsch@unibas.ch.

Abstract

Obernier et al. (2018) show that the primary mode of division of adult ventricular-subventricular zone (V-SVZ) neural stem cells is symmetric, with the majority generating two non-stem cell progeny, and a minority self-renewing. This discovery has important implications for understanding stem cell dynamics and adult neurogenesis.

PMID:
29673477
DOI:
10.1016/j.neuron.2018.04.005
[Indexed for MEDLINE]
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