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Immunity. 2018 Apr 17;48(4):608-613. doi: 10.1016/j.immuni.2018.03.022.

Systems Medicine in Chronic Inflammatory Diseases.

Author information

1
Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Electronic address: j.schultze@uni-bonn.de.
2
Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany; Department of MedicineI, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, 24105 Kiel, Germany. Electronic address: p.rosenstiel@mucosa.de.

Abstract

Chronic inflammatory diseases represent an increasing medical burden, yet neither tools to predict the individual disease course nor causal cures are at hand. We discuss opportunities for systems medicine to derive precise, individualized disease models and outline the European consortium SYSCID as part of the roadmap to clinical practice.

PMID:
29669240
DOI:
10.1016/j.immuni.2018.03.022
[Indexed for MEDLINE]

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