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Folia Med (Plovdiv). 2018 Mar 1;60(1):170-174. doi: 10.1515/folmed-2017-0064.

The Skin and the Eye - Herpes Zoster Ophthalmicus in a Healthy 18-month-old Toddler.

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Department of Infectious Disease, Parasitology and Tropical Medicine, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.
Department of Ophthalmology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.


Herpes zoster, caused by reactivation of varicella-zoster virus, is uncommon in infancy. Even more uncommon is herpes zoster ophthalmicus, defined as herpes zoster of the ophthalmic branch of the fifth cranial nerve. Among healthy children, primary varicella-zoster virus infection during gestation as a result of maternal varicella or the first year of life is the major risk factor for development of herpes zoster in a relatively young age. Here we present an unusual case of herpes zoster ophthalmicus with dissemination in an immunocompetent toddler with favorable outcome. The child's mother contracted chickenpox in late pregnancy and her son was very likely infected with varicella-zoster virus in utero. During a two-year follow-up the child vision was normal and there was no evidence of post herpetic neuralgia.


herpes zoster ophthalmicus; infancy; varicella-zoster virus


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