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Curr Cardiol Rev. 2018;14(3):164-174. doi: 10.2174/1573403X14666180416115428.

Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem.

Author information

1
Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
2
Laboratory of Allergology and Clinical Immunology, State University of Medicine and Pharmacy «Nicolae Testemitanu», Chisinau, Moldova, Republic of.
3
Federal State Budgetary Institution "Scientific Centre for Expert Evaluation of Medical Products" of the Ministry of Health of the Russian Federation, Moscow, Russian Federation.

Abstract

The burden of cardiovascular and metabolic diseases is increasing with every year. Although the management of these conditions has improved greatly over the years, it is still far from perfect. With all of this in mind, there is a need for new methods of prophylaxis and treatment. Coenzyme Q10 (CoQ10) is an essential compound of the human body. There is growing evidence that CoQ10 is tightly linked to cardiometabolic disorders. Its supplementation can be useful in a variety of chronic and acute disorders. This review analyses the role of CoQ10 in hypertension, ischemic heart disease, myocardial infarction, heart failure, viral myocarditis, cardiomyopathies, cardiac toxicity, dyslipidemia, obesity, type 2 diabetes mellitus, metabolic syndrome, cardiac procedures and resuscitation.

KEYWORDS:

Coenzyme Q10; cardiac procedures and resuscitation; cardiac toxicity; cardiomyopathies; dyslipidemia; heart failure; hypertension; ischemic heart disease; metabolic syndrome; myocardial infarction; obesity; type 2 diabetes mellitus; viral myocarditis.

PMID:
29663894
PMCID:
PMC6131403
[Available on 2019-08-01]
DOI:
10.2174/1573403X14666180416115428
[Indexed for MEDLINE]

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