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J Asian Nat Prod Res. 2019 Jul;21(7):597-602. doi: 10.1080/10286020.2018.1460363. Epub 2018 Apr 16.

Anti-inflammatory lupane triterpenoids from Menyanthes trifoliata.

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a School of Pharmacy , Anhui University of Chinese Medicine, Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei 230012 , China.
b School of Pharmaceutical Sciences , South-Central University for Nationalities , Wuhan 430074 , China.


A new lupane triterpenoid, 23-O-trans-feruloylcylicodiscic acid (1), as well as four known analogues (25), was isolated from the EtOAc fraction of Menyanthes trefoliata. The structure of compound 1 was elucidated on the basis of extensive spectroscopic analysis, including 2D NMR data. The structures of the known compounds were established by comparison of their spectroscopic data with that in the literature. Compounds 1, 2, and 4 exhibited certain anti-NO production activities.


; Gentianaceae; anti-NO production; lupane triterpenoid

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