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Fiziol Zh SSSR Im I M Sechenova. 1988 Jan;74(1):118-23.

[Role of brain serotonin in the regulation of sexual maturation in male rats].

[Article in Russian]


The effect of decrease of the brain serotonin level in different periods of prepubertal development on sexual maturation of male rats, was studied. Injections of p-CPA on the 30th and 34th days of life activated the endocrine function of testis in 60-day old animals. Injections of p-CPA later in life, on the 40th and 44th days, delayed sexual maturation as revealed by a decrease of spermatogenesis and endocrine function of testis. The data obtained suggest that serotonin has a dual role in regulation of the rate of sexual maturation in different periods of prepubertal age.

[Indexed for MEDLINE]

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