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J Neuroendocrinol. 2018 Apr 14:e12600. doi: 10.1111/jne.12600. [Epub ahead of print]

The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond":Unresolved questions, challenges and future directions for the field.

Author information

1
Department of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson, MS, 39216-4505, USA.
2
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, 39216-4505, USA.
3
Departments of Obstetrics,  Gynecology and Physiology & Biophysics, University of Washington, Box 357290 Seattle, WA 98195-7290, USA.
4
Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA.
5
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
6
Department of Physiology, Pharmacology and Neuroscience, West Virginia University, Morgantown, West Virginia, 26506, USA.
7
Reproductive Physiology Group, Department of Physiology, Development, Neuroscience, University of Cambridge, Cambridge, UK.
8
Howard Hughes Medical Institute, University of Washington, Seattle, WA, 98195, USA.
9
University of California, San Diego, Department of Obstetrics& Gynecology and Reproductive Sciences, La Jolla, CA, USA.
10
Endocrinology and Reproductive Physiology Training Program, University of Wisconsin-Madison, Madison, WI, 53715, USA.
11
Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR 97239 and Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA.
12
Centre for Neuroendocrinology and Department of Physiology, University of Otago School of Biomedical Science, Dunedin, 9054, New Zealand.
13
Department of Pediatrics, Rutgers University - Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA.
14
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
15
Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Department of Cell Biology, Physiology and Immunology, University of Córdoba; and Hospital Universitario Reina Sofia, 14004 Cordoba, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 14004Córdoba, Spain.
16
Section of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK.
17
Harvard Reproductive Sciences Center and Reproductive Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
18
Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
19
Department of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53715, USA.
20
Department of Pediatrics, University of Wisconsin-Madison, Madison, WI 53715, USA.

Abstract

The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond" was held March 30-31 at the Rosen Centre Hotel in Orlando, Florida, providing an international forum for multidisciplinary scientists to meet and share cutting-edge research on kisspeptin biology and its relevance to human health and disease. The meeting built upon previous world conferences focused on the role of kisspeptin and associated peptides in the control of gonadotropin-releasing hormone (GnRH) secretion and reproduction. Based on recent discoveries, the scope of this meeting was expanded to include functions of kisspeptin and related peptides in other physiological systems including energy homeostasis, pregnancy, ovarian and uterine function, and thermoregulation. In addition, discussions addressed the translation of basic knowledge of kisspeptin biology to the treatment of disease, with the goal of seeking consensus about the best approaches to improve human health. The two-day meeting featured a non-traditional structure, with each day starting with poster sessions followed by lunch discussions and facilitated large-group sessions with short presentations to maximize the exchange of new, unpublished data. Topics were identified by a survey prior to the meeting, and focused on major unresolved questions, important controversies, and future directions in the field. Finally, career development activities provided mentoring for trainees and junior investigators, and networking opportunities for those individuals with established researchers in the field. Overall, the meeting was rated as a success by attendees and covered a wide range of lively and provocative discussion topics on the changing nature of the field of "kisspeptinology" and its future. This article is protected by copyright. All rights reserved.

KEYWORDS:

Conference; GnRH; International; Kisspeptin; Neuroendocrine

PMID:
29656508
PMCID:
PMC6461527
[Available on 2019-10-14]
DOI:
10.1111/jne.12600

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