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Fertil Steril. 1988 Apr;49(4):666-9.

Insulin-like growth factor-I (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study.

Author information

1
Department of Human Anatomy, University of Florence, Italy.

Abstract

Using specific monoclonal antibodies, the authors studied the distribution of insulin growth factor-I (IGF-I) and its receptor in normal human testis by immunostaining techniques. IGF-I was preferentially localized in Sertoli cells. Less evident positivity was found in primary spermatocytes. In the interstitium some Leydig cells were positive for IGF-I. The major positivity for the IGF-I receptor was found in secondary spermatocytes and early spermatids, whereas Sertoli cells were less positive. An intense positivity was found in some Leydig cells.

PMID:
2965033
DOI:
10.1016/s0015-0282(16)59837-9
[Indexed for MEDLINE]

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