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Ann Endocrinol (Paris). 2018 Jun;79(3):153-156. doi: 10.1016/j.ando.2018.03.012. Epub 2018 Apr 9.

Are Cushing's disease patients curable?

Author information

1
Service des maladies endocriniennes et métaboliques, centre de référence des maladies rares de la surrénale, hôpital Cochin, faculté de médecine Paris-Descartes, université Paris 5, 24, rue du Faubourg-St-Jacques, 75014 Paris, France. Electronic address: xavier.bertagna@aphp.fr.

Abstract

Treatment of Cushing's disease remains a challenge. Whereas pituitary surgery can "cure" the patient and restore a completely normal pituitary adrenal axis, there are immediate failures and late recurrences which ultimately require alternate therapeutic approaches. These are numerous, but so are their drawbacks, and all appear to be "default options". For the future, pituitary adenoma has to remain the "reasonable obsession" of efficient and optimistic therapists….

KEYWORDS:

Chirurgie surrénalienne; Cushing's disease; Fonction hypophyso-surrénalienne; Maladie de Cushing; Pituitary adrenal axis; Pituitary surgery

PMID:
29650226
DOI:
10.1016/j.ando.2018.03.012
[Indexed for MEDLINE]

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