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Pediatr Dermatol. 2018 May;35(3):e202-e203. doi: 10.1111/pde.13480. Epub 2018 Apr 11.

Colchicine may be of therapeutic benefit in prurigo pigmentosa.

Author information

1
Department of Dermatology, Medical Faculty, Dicle University, Diyarbakır, Turkey.
2
Department of Pathology, Medical Faculty, Dicle University, Diyarbakır, Turkey.
3
Kocaköy Family Health Center, Diyarbakır, Turkey.
4
Department of Dermatology, İzmir Katip Çelebi University, İzmir, Turkey.

Abstract

Prurigo pigmentosa (PP) is a rare inflammatory skin disease. Neutrophil-mediated inflammation is considered to be responsible for the etiopathogenesis of PP. We consider that colchicine may be an effective agent in the treatment of PP since it exerts an antiinflammatory effect by inhibiting neutrophil chemotaxis. Further studies are required to verify whether colchicine is an effective treatment option for PP.

KEYWORDS:

pharmacology; pruritus; therapy-systemic

PMID:
29644750
DOI:
10.1111/pde.13480
[Indexed for MEDLINE]

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