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Dev Cell. 2018 Apr 9;45(1):1-2. doi: 10.1016/j.devcel.2018.03.014.

HCMV Assembly Is Totally Tubular.

Author information

1
Institute for Molecular Virology and McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: smmalone2@wisc.edu.
2
Institute for Molecular Virology and McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: rfkalejta@wisc.edu.

Abstract

Microtubules are normally organized at centrosomes, but other sites can also serve as microtubule organizing centers (MTOCs). In this issue of Developmental Cell, Procter et al. (2018) show that the human cytomegalovirus virion assembly compartment acts as a dynamic Golgi-derived MTOC where EB3 nucleates microtubules and regulates infectious virion production.

PMID:
29634930
DOI:
10.1016/j.devcel.2018.03.014
[Indexed for MEDLINE]

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