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Liver Transpl. 2018 Jun;24(6):831-840. doi: 10.1002/lt.25072.

Should organs from hepatitis C-positive donors be used in hepatitis C-negative recipients for liver transplantation?

Author information

1
Multiorgan Transplant Program, University of Toronto, Toronto, Canada.
2
Liver Transplantation and Hepatology Unit, La Fe University Hospital, Universidad de Valencia, Valencia, Spain.

Erratum in

Abstract

Given the scarcity of donated organs and the frequency of death on the waiting list, strategies that could improve the available supply of high-quality liver grafts are much needed. Direct-acting antiviral agent (DAA) regimens have proved to be highly effective to treat hepatitis C virus (HCV), even in the setting of posttransplantation. The question arises as to whether transplant communities should consider the utilization of HCV-positive donors into HCV-negative recipients. This review summarizes risk of transmission, treatment options with success rate, and ethical considerations for usage of HCV-positive donors. Liver Transplantation 24 831-840 2018 AASLD.

PMID:
29624894
DOI:
10.1002/lt.25072
[Indexed for MEDLINE]

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