Send to

Choose Destination
Psychooncology. 2018 Jul;27(7):1772-1779. doi: 10.1002/pon.4726. Epub 2018 Apr 27.

Cost-utility analysis of meaning-centered group psychotherapy for cancer survivors.

Author information

Department of Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
IDC Center for Psychological Care for Cancer Patients, OLVG Hospital, Amsterdam, The Netherlands.
Department of Otolaryngology-Head and Neck Surgery, Cancer Center Amsterdam (CCA), VU University Medical Center, Amsterdam, The Netherlands.
Department of Psychology, University of Roehampton, London, UK.
Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
VU University Medical Center, Epidemiology & Biostatistics, Amsterdam, The Netherlands.



Meaning-centered group psychotherapy for cancer survivors (MCGP-CS) improves meaning, psychological well-being, and mental adjustment to cancer and reduces psychological distress. This randomized controlled trial was conducted to investigate the cost-utility of MCGP-CS compared with supportive group psychotherapy (SGP) and care-as-usual (CAU).


In total, 170 patients were randomized to MCGP-CS, SGP, or CAU. Intervention costs, direct medical and nonmedical costs, productivity losses, and health-related quality of life were measured until 6 months follow-up, using the TIC-P, PRODISQ, data from the hospital information system, and the EQ-5D. The cost-utility was calculated by comparing mean cumulative costs and quality-adjusted life years (QALYs).


Mean total costs ranged from €4492 (MCGP-CS) to €5304 (CAU). Mean QALYs ranged .507 (CAU) to .540 (MCGP-CS). MCGP-CS had a probability of 74% to be both less costly and more effective than CAU, and 49% compared with SGP. Sensitivity analyses showed these findings are robust. If society is willing to pay €0 for one gained QALY, MCGP-CS has a 78% probability of being cost-effective compared with CAU. This increases to 85% and 92% at willingness-to-pay thresholds of €10 000 and €30 000, which are commonly accepted thresholds.


MCGP-CS is highly likely a cost-effective intervention, meaning that there is a positive balance between the costs and gains of MCGP-CS, in comparison with SGP and CAU.


MCGP; cancer; cost-effectiveness; cost-utility analysis; existential; group psychotherapy; meaning; meaning-centered psychotherapy; oncology; psychotherapy

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center