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PLoS One. 2018 Apr 4;13(4):e0195431. doi: 10.1371/journal.pone.0195431. eCollection 2018.

HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study.

Author information

1
HIV/STI Unit, Institute of Tropical Medicine, Antwerp, Belgium.
2
Division of Infectious Diseases and HIV Medicine, University of Cape Town, Cape Town, South Africa.

Abstract

BACKGROUND:

HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Understanding the factors responsible for this heterogeneity in HIV spread may guide prevention efforts.

METHODS:

We evaluated the relationship between HIV prevalence by ethnic group and a range of risk factors as well as the prevalence of herpes simplex virus-2 (HSV-2), syphilis and symptomatic STIs in the 2004/2005 Uganda HIV/AIDS Sero-Behavioural Survey-a two stage, nationally representative, population based survey of 15-59-year-olds. Spearman's correlation was used to assess the relationship between HIV prevalence and each variable.

RESULTS:

There was a positive association between HIV prevalence and HSV-2, symptomatic STIs and high-risk sex (sex with a non-cohabiting, non-marital partner) for women. Non-significant positive associations were present between HIV and high-risk sex for men and lifetime number of partners for men and women.

CONCLUSION:

Variation in sexual behavior may contribute to the variations in HIV, HSV-2 and other STI prevalence by ethnic group in Uganda. Further work is necessary to delineate which combinations of risk factors determine differential STI spread in Uganda.

PMID:
29617423
PMCID:
PMC5884562
DOI:
10.1371/journal.pone.0195431
[Indexed for MEDLINE]
Free PMC Article

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