Format

Send to

Choose Destination
Chem Commun (Camb). 2018 Apr 17;54(32):3944-3946. doi: 10.1039/c8cc01427b.

An intramolecular antiparallel G-quadruplex formed by human telomere RNA.

Author information

1
Medical Sciences, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyo-take, Miyazaki 889-1692, Japan. xuyan@med.miyazaki-u.ac.jp.

Abstract

Until now, RNA G-quadruplexes were believed to only adopt a parallel G-quadruplex structure. In this study, we describe the first observation of an antiparallel RNA G-quadruplex formed by human telomere RNA. This newly described topology is of great interest as it shows that RNA G-quadruplexes can also be polymorphic and adopt structures that are different from the parallel configuration.

PMID:
29610814
DOI:
10.1039/c8cc01427b
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Royal Society of Chemistry
Loading ...
Support Center