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Infect Control Hosp Epidemiol. 2018 Jun;39(6):741-745. doi: 10.1017/ice.2018.44. Epub 2018 Apr 2.

Effect of Intranasal Mupirocin Prophylaxis on Methicillin-Resistant Staphylococcus aureus Transmission and Invasive Staphylococcal Infections in a Neonatal Intensive Care Unit.

Author information

1
1Division of Pediatric Infectious Diseases,Mayo Clinic,Rochester,Minnesota.
2
2Department of Pediatrics,University of Louisville,Louisville,Kentucky.
3
3Norton Children's Hospital,Louisville,Kentucky.
4
4Norton Healthcare,Louisville,Kentucky.

Abstract

The use of monthly intranasal mupirocin was associated with a significant reduction in the rate of methicillin-resistant Staphylococcus aureus transmission and Staphylococcus aureus invasive infection in a large neonatal intensive care unit. Resistance to mupirocin emerged over time, but it was rare and was not associated with adverse clinical outcomes.Infect Control Hosp Epidemiol 2018;39:741-745.

PMID:
29606181
DOI:
10.1017/ice.2018.44
[Indexed for MEDLINE]

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