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J Cataract Refract Surg. 2018 Mar;44(3):323-328. doi: 10.1016/j.jcrs.2017.12.023. Epub 2018 Mar 28.

Patient satisfaction with epithelium-off corneal crosslinking.

Author information

1
From the Cornea Research Foundation of America (M.O. Price) and the Price Vision Group (Feng, F.W. Price), Indianapolis, Indiana, USA. Electronic address: mprice@cornea.org.
2
From the Cornea Research Foundation of America (M.O. Price) and the Price Vision Group (Feng, F.W. Price), Indianapolis, Indiana, USA.

Abstract

PURPOSE:

To assess patient satisfaction with corneal crosslinking (CXL).

SETTING:

Price Vision Group, Indianapolis, Indiana, USA.

DESIGN:

Prospective case series.

METHODS:

Patients treated with the Dresden protocol or accelerated epithelium-off CXL during an 8-year period were invited to participate in an electronic survey.

RESULTS:

Of the 552 patients who were invited to participate, 448 (80% response rate) completed the electronic survey. The median time from CXL to survey completion was 3.5 years (range 1 to 9 years). The participants were 73% men; 78% had keratoconus, 22% had post-refractive surgical ectasia, and 44% had bilateral treatment. Comparable proportions of those treated with standard and accelerated CXL reported that it halted disease progression (88% versus 87%, respectively, P = .78). A younger treatment age was associated with higher perceived efficacy (P = .0003). The proportion who considered CXL effective was 93% among those with mild keratoconus, 86% with moderate to severe keratoconus, and 78% with post-refractive surgical ectasia (P = .0004). Regarding vision, 41% reported improvement after CXL, 46% noted no change, and 14% perceived continued decline. The mean satisfaction score was 8.8 ± 1.7 (SD) on a scale of 1 (would not recommend CXL) to 10 (definitely would recommend) among those treated for keratoconus and 7.6 ± 2.5 among those treated for ectasia after keratorefractive surgery (P < .0001). Eleven (1.7%) of 644 treated eyes had subsequent keratoplasty.

CONCLUSION:

Most patients considered CXL effective. The perceived efficacy did not vary significantly as a function of follow-up time (P = .90), suggesting no discernible fading of effect over the 1- to 9-year follow-up.

PMID:
29605283
DOI:
10.1016/j.jcrs.2017.12.023

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