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Viruses. 2018 Mar 29;10(4). pii: E158. doi: 10.3390/v10040158.

1st German Phage Symposium-Conference Report.

Author information

1
Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany. irene.huber@uni-hohenheim.de.
2
Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany. Katerina.Potapova@uni-hohenheim.de.
3
Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany. andikuhn@uni-hohenheim.de.
4
Institute of Microbiology, University of Hohenheim, 70599 Stuttgart, Germany. andikuhn@uni-hohenheim.de.
5
Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany. Herbert.schmidt@uni-hohenheim.de.
6
Institute of Food Science and Biotechnology, University of Hohenheim, 70599 Stuttgart, Germany. Herbert.schmidt@uni-hohenheim.de.
7
Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany. j.hinrichs@uni-hohenheim.de.
8
Institute of Food Science and Biotechnology, University of Hohenheim, 70599 Stuttgart, Germany. j.hinrichs@uni-hohenheim.de.
9
Leibniz-Institute DSMZ—German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany. Chr@dsmz.de.
10
Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany. Wolfgang.Beyer@uni-hohenheim.de.
11
Institute of Animal Sciences, University of Hohenheim, 70599 Stuttgart, Germany. Wolfgang.Beyer@uni-hohenheim.de.

Abstract

In Germany, phage research and application can be traced back to the beginning of the 20th century. However, with the triumphal march of antibiotics around the world, the significance of bacteriophages faded in most countries, and respective research mainly focused on fundamental questions and niche applications. After a century, we pay tribute to the overuse of antibiotics that led to multidrug resistance and calls for new strategies to combat pathogenic microbes. Against this background, bacteriophages came into the spotlight of researchers and practitioners again resulting in a fast growing "phage community". In October 2017, part of this community met at the 1st German Phage Symposium to share their knowledge and experiences. The participants discussed open questions and challenges related to phage therapy and the application of phages in general. This report summarizes the presentations given, highlights the main points of the round table discussion and concludes with an outlook for the different aspects of phage application.

KEYWORDS:

Germany; antimicrobial resistance (AMR); bacteriophage; co-evolution; horizontal gene transfer; industrial phage application; phage; phage therapy

PMID:
29596346
PMCID:
PMC5923452
DOI:
10.3390/v10040158
[Indexed for MEDLINE]
Free PMC Article

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