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Mikrochim Acta. 2018 Jan 24;185(2):124. doi: 10.1007/s00604-017-2663-8.

Ultrathin NiCo2O4 nanowalls supported on a 3D nanoporous gold coated needle for non-enzymatic amperometric sensing of glucose.

Author information

1
State Key Laboratory of Automotive Simulation and Control, Department of Materials Science, Jilin University, Changchun, 130012, China.
2
The Second Hospital of Jilin University, Changchun, 130041, People's Republic of China.
3
The First Hospital of Jilin University, Changchun, 130041, People's Republic of China.
4
Key Laboratory for Renewable Energy, Institute of Physics, Chinese Academy of Sciences, Beijing, 100190, China.
5
State Key Laboratory of Automotive Simulation and Control, Department of Materials Science, Jilin University, Changchun, 130012, China. xqcui@jlu.edu.cn.

Abstract

A disposable needle-type of hybrid electrode was prepared from a core of stainless steel needle whose surface was modified with a 3D nanoporous gold/NiCo2O4 nanowall hybrid structure for electrochemical non-enzymatic glucose detection. This hybrid electrode, best operated at 0.45 V (vs. SCE) in solutions of pH 13 has a linear response in the 0.01 to 21 mM glucose concentration range, a response time of <1 s, and a 1 μM detection limit (at an S/N ratio of 3). The remarkable enhancement compared to the solid gold/NiCo2O4 and stainless steel/NiCo2O4 hybrid electrodes in electrochemical performance is assumed to originate from the good electrical conductivity and large surface area of the hybrid electrode, which enhance the transport of mass and charge during electrochemical reactions. This biosensor was also applied to real sample analysis with little interferences. The electrode is disposable and considered to be a promising tool for non-enzymatic sensing of glucose in a variety of practical situations. Graphical abstract Ultrathin NiCo2O4 nanowalls supported on nanoporous gold that is coated on a stainless steel needle was fabricated for sensitive non-enzymatic amperometric sensing of glucose.

KEYWORDS:

Biosensor; Blood serum; Electrocatalyst; Electrochemical alloying/dealloying; Electrochemical glucose biosensor; Electrodeposition; Glucose electrooxidation; Gold needle electrode; NiCo2O4 nanosheets; Stainless steel

PMID:
29594748
DOI:
10.1007/s00604-017-2663-8
[Indexed for MEDLINE]

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