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Best Pract Res Clin Obstet Gynaecol. 2018 May;49:117-126. doi: 10.1016/j.bpobgyn.2018.02.002. Epub 2018 Feb 23.

Building consensus and standards in fetal growth restriction studies.

Author information

1
University Medical Center Groningen, University of Groningen, PO Box 30001, CB20, 9700 RB, Groningen, The Netherlands. Electronic address: s.j.gordijn@umcg.nl.
2
University Medical Center Groningen, University of Groningen, PO Box 30001, CB20, 9700 RB, Groningen, The Netherlands. Electronic address: irenebeune@hotmail.com.
3
Academisch Medisch Centrum, Universiteit van Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands. Electronic address: j.w.ganzevoort@amc.uva.nl.

Abstract

Fetal growth restriction is a pathologic condition in which the fetus fails to reach its biologically based growth potential. There is inconsistency in terminology, definition, monitoring, and management, both in clinical practice and in the existing literature. This hampers interpretation and comparison of cohorts and studies. Standardization is essential. With the lack of a golden standard, or the opportunity to come to empirical evidence, consensus procedures can help to establish standardization. Consensus procedures provide no new information but formulate an agreement (as second best in the absence of robust evidence) for clinical and/or research practice on the basis of existing data. Consensus agreements need to be updated when new evidence becomes available and can change over time. In this chapter, we address the different issues that lack uniformity in FGR studies and management. Furthermore, we discuss several consensus methods and recent consensus procedures regarding fetal growth restriction.

KEYWORDS:

Consensus; Core outcome set; Delphi procedure; Fetal growth restriction; Small for gestational age

PMID:
29576470
DOI:
10.1016/j.bpobgyn.2018.02.002
[Indexed for MEDLINE]

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