Complete Genome Sequence of the Live Attenuated Vaccine Strain Brucella melitensis Rev.1

Mali Salmon-Divon; Menachem Banai; Svetlana Bardenstein; Shlomo E Blum; David Kornspan

doi:10.1128/genomeA.00175-18

Complete Genome Sequence of the Live Attenuated Vaccine Strain Brucella melitensis Rev.1

Genome Announc. 2018 Mar 22;6(12):e00175-18. doi: 10.1128/genomeA.00175-18.

Authors

Mali Salmon-Divon¹, Menachem Banai², Svetlana Bardenstein², Shlomo E Blum², David Kornspan³

Affiliations

¹ Genomic Bioinformatics Laboratory, Department of Molecular Biology, Ariel University, Ariel, Israel malisa@ariel.ac.il davidko@moag.gov.il.
² Department of Bacteriology, Kimron Veterinary Institute, Bet Dagan, Israel.
³ Department of Bacteriology, Kimron Veterinary Institute, Bet Dagan, Israel malisa@ariel.ac.il davidko@moag.gov.il.

Abstract

Live attenuated vaccines are essential elements in control programs for the prevention of brucellosis. Here, we report the whole-genome sequence of the original Elberg Brucella melitensis Rev.1 vaccine strain, passage 101 (1970). Commercial lines of the original strain have been successfully used in small ruminants worldwide.