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Neuron. 2018 Mar 21;97(6):1200-1202. doi: 10.1016/j.neuron.2018.03.013.

Sleep, Anesthesia, and Plasticity.

Author information

1
Department of Psychiatry and Neuroscience, Université Laval, Québec G1V 0A6, Canada; CERVO Brain Research Center, Université Laval, Québec G1J 2G3, Canada. Electronic address: Igor.Timofeev@fmed.ulaval.ca.
2
CERVO Brain Research Center, Université Laval, Québec G1J 2G3, Canada.

Abstract

Two theories continuously clash: does sleep downscale or potentiate synapses? A study in Neuron by González-Rueda et al. (2018) demonstrates overall synaptic depression during anesthesia-induced slow-wave activity. Because anesthesia is typically associated with amnesia, the question of whether slow-wave sleep potentiates or depresses cortical synapses remains open.

PMID:
29566787
DOI:
10.1016/j.neuron.2018.03.013
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