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Viruses. 2018 Mar 22;10(4). pii: E143. doi: 10.3390/v10040143.

Novel Parvoviruses from Wild and Domestic Animals in Brazil Provide New Insights into Parvovirus Distribution and Diversity.

Author information

1
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. wmarciel@usp.br.
2
MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. wmarciel@usp.br.
3
MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. t.dennis.1@research.gla.ac.uk.
4
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. marcilio_jorge@hotmail.com.
5
Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil. jansentequila@usp.br.
6
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. sabinogsj@usp.br.
7
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. felipegmaia@gmail.com.
8
Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil. felipegmaia@gmail.com.
9
Universidade Federal da Fronteira Sul, Passo Fundo, RS 99010-200, Brazil. gacrani@gmail.com.
10
Universidade Estadual do Centro-Oeste, Guarapuava 85015-430, Paraná, Brazil. adriano.carrasco@gmail.com.
11
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. mafarignoli@hotmail.com.
12
MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. sejal.modha@glasgow.ac.uk.
13
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. luiz_carlos_vieira@hotmail.com.
14
Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil. tatiometto@usp.br.
15
Faculty of Veterinary Medicine, São Paulo State University, Araçatuba, SP 16050-680, Brazil. lhqueiroz@fmva.unesp.br.
16
Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, SP, Brazil. eldurigo@usp.br.
17
Center for Technological Innovations, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará 67030-000, Pará, Brazil. marcionunesbrasil@yahoo.com.br.
18
Virology Research Center, Ribeirão Preto Medical School, University of São Paulo,14049-900 Ribeirão Preto, SP, Brazil. ltmfigue@fmrp.usp.br.
19
MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. robert.gifford@glasgow.ac.uk.

Abstract

Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified. In this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses infecting wild and domestic animals in Brazil. We identified 21 parvovirus sequences (including twelve nearly complete genomes and nine partial genomes) in samples derived from rodents, bats, opossums, birds and cattle in Pernambuco, São Paulo, Paraná and Rio Grande do Sul states. These sequences were investigated using phylogenetic and distance-based approaches and were thereby classified into eight parvovirus species (six of which have not been described previously), representing six distinct genera in the subfamily Parvovirinae. Our findings extend the known biogeographic range of previously characterized parvovirus species and the known host range of three parvovirus genera (Dependovirus, Aveparvovirus and Tetraparvovirus). Moreover, our investigation provides a window into the ecological dynamics of parvovirus infections in vertebrates, revealing that many parvovirus genera contain well-defined sub-lineages that circulate widely throughout the world within particular taxonomic groups of hosts.

KEYWORDS:

Parvoviridae; parvovirus; ssDNA viruses; zoonotic viruses

PMID:
29565808
PMCID:
PMC5923437
DOI:
10.3390/v10040143
[Indexed for MEDLINE]
Free PMC Article

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