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J Assist Reprod Genet. 2018 May;35(5):753-756. doi: 10.1007/s10815-018-1159-8. Epub 2018 Mar 21.

Platelet-rich plasma therapy and reproductive medicine.

Author information

1
Federal University of Rio Grande do Sul, Porto Alegre, Brazil. Adriana.bosmikich@gmail.com.
2
RDO Medical Diagnosis, São Paulo, Brazil.
3
Nilo Frantz Human Reproduction Center, Porto Alegre, Brazil.

Abstract

Reports on clinical uses of platelet-rich plasma (PRP) have dramatically increased in the last decade. Indications for PRP therapy range from muscle and skeletal injuries to hair re-growth. More recently evidences have shown its positive effects in promoting endometrial and follicular growth and gestation in assisted reproduction cycles. We discuss the putative role of PRP on endometrial receptivity, with a brief history of its applications in research and clinical therapies. Despite its widespread uses in medicine, the mechanisms through which PRP exerts its regenerative effects are only postulated, not based on scientific data. There is an unmet need for advanced research to corroborate present findings in the clinical scenario.

PMID:
29564738
PMCID:
PMC5984895
[Available on 2019-05-01]
DOI:
10.1007/s10815-018-1159-8
[Indexed for MEDLINE]

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