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Curr Drug Discov Technol. 2018 Mar 19. doi: 10.2174/1570163815666180320111937. [Epub ahead of print]

Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery.

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Department of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511. Egypt.
Phytomedicine, Biochemical Toxicology, and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, 360001. Nigeria.
Gastrointestinal and Liver Disease Research Center, Guilan University of Medical Sciences, Rasht. Iran.
Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, University of Sadat City. Egypt.
Chemistry Department, Faculty of Science, An-Najah National University, P.O. Box. 7, 415 Nablus. Palestinian Territory, Occupied.
Department of Pharmacology, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511. Egypt.
Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz. Iran.
Department of Histology and Cytology, Faculty of Veterinary Medicine, Damanhour University, Damanhour. Egypt.
Hematology/Pediatric Oncology, King Abdulaziz University Hospital and Scientific Chair of Yousef Abdullatif Jameel of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah 21589. Saudi Arabia.
Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, NY 12144, United States.


Phoenix dactylifera is a useful traditional medicinal plant, mainly the fruit is used, which is the edible part of the plant (Ajwa date). It is now considered to be a valuable source of natural medicinal products against various diseases. Phytochemical investigations have shown that the fruit contains anthocyanins, phenolics, sterols, carotenoids, and flavonoids. The fruits are a rich source of carbohydrates, vitamins, and proteins. P. dactylifera is considered as a complete diet because it also contains different fatty acids, amino acids, proteins, and steroidal substances. This review highlights the phytochemical composition, nutritional significance, and potential health benefits of P. dactylifera and discusses its potential as a functional food for disease prevention, management, and treatment.


Biological activities; Future directions ; Phoenix dactylifera; Phytochemicals

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