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Fertil Steril. 2018 May;109(5):866-871. doi: 10.1016/j.fertnstert.2018.01.015. Epub 2018 Mar 16.

Association between use of marijuana and time to pregnancy in men and women: findings from the National Survey of Family Growth.

Author information

1
Department of Urology, Stanford University School of Medicine, Stanford, California.
2
Department of Family Science, School of Public Health, University of Maryland, College Park, Maryland.
3
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.
4
Department of Urology, Stanford University School of Medicine, Stanford, California. Electronic address: eisenberg@stanford.edu.

Abstract

OBJECTIVE:

To determine if regular use of marijuana has an impact on time to pregnancy.

DESIGN:

Retrospective review of cross-sectional survey data from male and female respondents aged 15-44 years who participated in the 2002, 2006-2010, and 2011-2015 National Survey of Family Growth.

SETTING:

Not applicable.

PARTICIPANT(S):

The National Survey of Family Growth is a nationally representative population-based sample derived from stratified multistage area probability sampling of 121 geographic areas in the U.S. Our analytic sample was participants who were actively trying to conceive.

INTERVENTION(S):

Exposure status was based on the respondents' answers regarding their marijuana use in the preceding 12 months.

MAIN OUTCOME MEASURE(S):

The main outcome was estimated time to pregnancy, which was hypothesized before analysis to be delayed by regular marijuana use.

RESULT(S):

A total of 758 male and 1,076 female participants responded that they were actively trying to conceive. Overall, 16.5% of men reported using any marijuana while attempting to conceive, versus 11.5% of women. The time ratio to pregnancy for never smokers versus daily users of marijuana in men was 1.08 (95% confidence interval 0.79-1.47) and in women 0.92 (0.43-1.95), demonstrating no statistically significant impact of marijuana use on time to pregnancy.

CONCLUSION(S):

Our study suggests that neither marijuana use nor frequency of marijuana use was associated with time to pregnancy for men and women.

KEYWORDS:

Fertility; infertility; marijuana

[Indexed for MEDLINE]

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