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Adv Food Nutr Res. 2018;84:57-102. doi: 10.1016/bs.afnr.2018.01.003. Epub 2018 Mar 7.

Novel Biosensors for the Rapid Detection of Toxicants in Foods.

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Laboratory of Inorganic & Analytical Chemistry, School of Chemical Engineering, Chemical Sciences, National Technical University of Athens, Athens, Greece.
Laboratory of Environmental Chemistry, University of Athens, Athens, Greece. Electronic address:
Laboratory of Simulation of Industrial Processes, School of Maritime and Industry, University of Piraeus, Piraeus, Greece.
Laboratory of Inorganic Chemistry, University of Athens, Athens, Greece; Technological Educational Institute of Peloponnese, Kalamata, Greece.


The modern environmental and food analysis requires sensitive, accurate, and rapid methods. The growing field of biosensors represents an answer to this demand. Unfortunately, most biosensor systems have been tested only on distilled water or buffered solutions, although applications to real samples are increasingly appearing in recent years. In this context, biosensors for potential food applications continue to show advances in areas such as genetic modification of enzymes and microorganisms, improvement of recognition element immobilization, and sensor interfaces. This chapter investigates the progress in the development of biosensors for the rapid detection of food toxicants for online applications. Recent progress in nanotechnology has produced affordable, mass-produced devices, and to integrate these into components and systems (including portable ones) for mass market applications for food toxicants monitoring. Sensing includes chemical and microbiological food toxicants, such as toxins, insecticides, pesticides, herbicides, microorganisms, bacteria, viruses and other microorganisms, phenolic compounds, allergens, genetically modified foods, hormones, dioxins, etc. Therefore, the state of the art of recent advances and future targets in the development of biosensors for food monitoring is summarized as follows: biosensors for food analysis will be highly sensitive, selective, rapidly responding, real time, massively parallel, with no or minimum sample preparation, and platform suited to portable and handheld nanosensors for the rapid detection of food toxicants for online uses even by nonskilled personnel.


Antibody based; Biosensors; Cell based; Electrochemical; Enzymatic; Food analysis; Food monitoring; Food toxicants; Molecularly imprinted polymers; Nanotechnology; Online applications; Optical

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