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Urology. 2018 Sep;119:137-139. doi: 10.1016/j.urology.2018.01.007. Epub 2018 Mar 13.

A Rare Case of Pediatric Vaginal Yolk Sac Tumor.

Author information

1
Department of Pediatric Urology, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.
2
Department of Pediatric Urology, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA. Electronic address: aylin.bilgutay@gmail.com.

Abstract

A 14-month-old girl was evaluated for intermittent vaginal bleeding. Vaginoscopy revealed a friable tumor, and biopsy results confirmed a yolk sac tumor. Alpha-fetoprotein was elevated (1386‚ÄČng/mL) at diagnosis but quickly normalized with chemotherapy. The patient remained tumor-free 12 months after diagnosis without the need for radical surgery. Although rare, malignant tumors of the vagina must be included in the differential diagnosis of prepubertal girls who present with vaginal bleeding. Primary yolk sac tumor of the vagina is seen in girls less than 3 years of age and is treated with chemotherapy with or without surgical excision. Prognosis is good with appropriate treatment.

PMID:
29548872
DOI:
10.1016/j.urology.2018.01.007
[Indexed for MEDLINE]

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