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Food Chem. 2018 Jul 15;254:377-389. doi: 10.1016/j.foodchem.2018.01.176. Epub 2018 Feb 1.

Lycium barbarum polysaccharides: Extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review.

Author information

1
Dipartimento di Medicina Sperimentale, Unità di Ricerca di Scienza dell'Alimentazione e Nutrizione Umana, Università degli Studi di Roma "La Sapienza", Viale del Policlinico, 155, 00161 Roma, Italy.
2
Dipartimento di Farmacia, Università "G. d'Annunzio" di Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.
3
Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma "La Sapienza", Piazzale Aldo Moro, 5, 00185 Roma, Italy.
4
Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma "La Sapienza", Piazzale Aldo Moro, 5, 00185 Roma, Italy. Electronic address: stefania.cesa@uniroma1.it.

Abstract

In the last decades, glycoconjugates from Lycium barbarum L. fruit (Goji berry) have received a great attention for their potential health-promoting effects. The present review includes a survey of extraction and purification methods of these bioactive molecules (L. barbarum polysaccharides, LBPs), along with a dissertation on the structural characterisation of the carbohydrate component. Furthermore, an overview of in vitro, in vivo and clinical studies concerning the hypoglycaemic and hypolipidaemic effects of isolated LBP fractions, is reported. The evidence suggests that these purified components of the Goji berry may be potentially useful as adjuvants in the treatment of diabetes and its correlated illnesses.

KEYWORDS:

Arabinogalactan proteins; Goji berry; Hypoglycaemic effects; Hypolipidaemic effects; Lycium barbarum polysaccharides

PMID:
29548467
DOI:
10.1016/j.foodchem.2018.01.176
[Indexed for MEDLINE]

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