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Biomed Opt Express. 2018 Feb 13;9(3):1111-1129. doi: 10.1364/BOE.9.001111. eCollection 2018 Mar 1.

Eye-motion-corrected optical coherence tomography angiography using Lissajous scanning.

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Computational Optics Group, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.
Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki 305-8531, Japan.


To correct eye motion artifacts in en face optical coherence tomography angiography (OCT-A) images, a Lissajous scanning method with subsequent software-based motion correction is proposed. The standard Lissajous scanning pattern is modified to be compatible with OCT-A and a corresponding motion correction algorithm is designed. The effectiveness of our method was demonstrated by comparing en face OCT-A images with and without motion correction. The method was further validated by comparing motion-corrected images with scanning laser ophthalmoscopy images, and the repeatability of the method was evaluated using a checkerboard image. A motion-corrected en face OCT-A image from a blinking case is presented to demonstrate the ability of the method to deal with eye blinking. Results show that the method can produce accurate motion-free en face OCT-A images of the posterior segment of the eye in vivo.


(100.0100) Image processing; (170.3880) Medical and biological imaging; (170.4470) Ophthalmology; (170.4500) Optical coherence tomography

Conflict of interest statement

YC, YJH: Topcon (F), Tomey Corporation (F), Nidek (F), KAO (F). SM, YY Topcon (F), Tomey Corporation (F, P), Nidek (F, P), KAO. YJH is currently employed by Koh Young Technology.

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